By Dr. Martin Pierre Marie Granier (auth.), Richard J. Robbins M.D., Shlomo Melmed M.D. (eds.)
The manuscripts during this quantity have been contributed via the audio system invited to the Acromegaly Centennial Symposium held in San Francisco, California in July 1986. The assembly was once geared up to commemorate the outline of acromegaly through the French health care professional Pierre Marie, in 1886. The contributors of the clinical Committee spent many hours aiding us in making sure a great assembly. The aid of Serono Symposia, united states in all stages of the making plans and execution of the assembly was once in actual fact favored and used to be hugely specialist. detailed popularity roust be prolonged to Professor Roger Guillemin of the Salk Institute, whosp curiosity in scientific background led him to dedicate loads of time and private cost in acquiring information regarding the lifetime of Pierre Marie. Dr. GuilIemin's presentation at the lifestyles and instances of Marie used to be a rare review of the cultural, social, and medical backgrounds during which Marie got here to explain the sickness, acromegaly. Dr. Guillemin' s findings, that have been awarded on the major dinner party in a the best option audiovisual presentation, have been sincerely the spotlight of the assembly and should lengthy be remembered through the attendees. We have been additionally venerated by means of the presence of Dr. Martine Pierre Marie Granier, the great-granddaughter of Pierre Harie. In her handle on the dinner party, Dr. Granier supplied numerous pleasant and intimate vignettes bearing on Pierre Marie, utilizing previous kinfolk documents and images. The clinical Committee needs to increase its gratitude to Dr. Granier for including immeasurably to the old surroundings of the meeting.
Read Online or Download Acromegaly: A Century of Scientific and Clinical Progress PDF
Similar clinical books
An absolutely up to date variation of a greatly revered vintage at the prognosis and administration of bronchial asthma in numerous sufferer subpopulations. although this 5th variation maintains to stress the definition, drugs, and use of bronchial asthma remedies, it additionally makes a speciality of the particular wishes sufferer, together with the pediatric sufferer, the pregnant sufferer, and the sufferer present process surgical procedure, in addition to at the perennial problems with workout and bronchial asthma, pulmonary aspergillosis, career, leisure drug use, and psychological/social issues.
Together with thirteen chapters, this e-book is uniformly written to supply good, matter-of-fact equipment for knowing and taking good care of sufferers with everlasting pacemakers, ICDs and CRT structures. Now enhanced and up to date, together with a brand new bankruptcy on programming and optimization of CRT units, this moment variation provides a large number of details in an simply digestible shape.
In recent times, the ryanodine receptor has emerged as a brand new and extremely promising goal for the therapy of numerous cardiovascular problems, together with cardiac arrhythmias and center failure. This quantity is the most up-tp-date booklet dedicated to the key intracellular calcium-release channel, the ryanodine receptor.
Even though a lot paintings is still performed towards realizing the factors of schizophrenia and attenuating its indicators, a transparent consensus has emerged that larger results are linked to early therapy. In Early scientific Intervention and Prevention in Schizophrenia, prime and across the world famous researchers evaluation what's identified in regards to the legal responsibility to schizophrenia, the way it progresses, what it appears like clinically-with an emphasis on a selected (proposed) syndrome of legal responsibility (schizotaxia)-and how most sensible it would be taken care of now and within the close to destiny.
- Clinical Pharmacology of Antianginal Drugs
- Recent Advances in Parkinson’S Disease: Translational and Clinical Research, 1st Edition
- Retinal Degeneration: Clinical and Laboratory Applications
- Cardiac Electrophysiology: Clinical Case Review
Additional info for Acromegaly: A Century of Scientific and Clinical Progress
Miami winter symposium. New York: Academic Press, 1980. Lewis UJ, Peterson SM, Bonewald LF, Seavey BK, VanderLaan WP. An interchain disulfide dimer of human growth hormone. J BioI Chem 1977; 252:3697. Schneider AB, Kowalski K, Russell J, Sherwood LM. Identification of the interchain disulfide bonds of dimeric human placental lactogen. J BioI Chem 1979; 254:3782. DeNoto FM, Moore DD, Goodman HM. Human growth hormone DNA sequence and mRNA structure: possible alternative splicing. Nucleic Acids Res 1981; 9:3719.
Wurzel J, Parks JS, Herd JE, et al. A gene deletion is responsible for absence of human chorionic somatomammotropin. DNA 1982; 1:251. 42. Parks JS. Organization and function of the growth hormone gene cluster. In: Raiti S, Tolman RA, eds. Human growth hormone. New York: Plenum, 1986:199. 43. Pavlakis GN, Hizuka N, Gorden P, et al. Expression of two human growth hormone genes in monkey cells infected by simian virus 40 recombinants. Proc Natl Acad Sci USA 1981; 78:7398. 44. Hizuka N, Hendricks CM, Pavlakis GN, et al.
The possibility exists, therefore, that when given to an animal, GH is cleaved either in the circulation or at the target organ to produce a diabetogenic fragment more active than GH itself. Evidence for another diabetogenic 31 substance also comes from the report by Hart et al. (40) who showed that a preparation of bovine GH with the greatest growth promoting activity was not the most diabetogenic fraction isolated from the pituitary. Another pituitary fraction rich in low molecular weight substances showed the greatest diabetogenic activity.